SCHEMBL557889

SCHEMBL557889

CCOC(=O)CN(C)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.55
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
LTA4H P09960 1/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPT P10636 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 2/20 0.44
PPID Q08752 1/20 0.43
GLA P06280 1/20 0.43
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7150239 0.98 SMN1; SMN2 (0.54) SMN1; SMN2MEN1KMT2ALTA4HALDH1A1
SCHEMBL21530451 0.87 SMN1; SMN2 (0.50) SMN1; SMN2MEN1KMT2ALTA4HALDH1A1
SCHEMBL10188370 0.86 SMN1; SMN2 (0.43) SMN1; SMN2MEN1KMT2ALTA4HALDH1A1
SCHEMBL28703573 0.86 RAB9A (0.45) SMN1; SMN2MEN1KMT2AALDH1A1KDM4E
SCHEMBL7448315 0.84 KMT2A (0.49) SMN1; SMN2KMT2AALDH1A1KDM4EMAPT
SCHEMBL11228033 0.84 MEN1 (0.41) SMN1; SMN2MEN1KMT2ALTA4HALDH1A1
SCHEMBL11464342 0.84 L3MBTL1 (0.45) SMN1; SMN2MEN1KMT2AALDH1A1MAPT
SCHEMBL4458579 0.84 SMN1; SMN2 (0.57) SMN1; SMN2MEN1KMT2ALTA4HALDH1A1
SCHEMBL8624227 0.84 SMN1; SMN2 (0.57) SMN1; SMN2MEN1KMT2ALTA4HALDH1A1
SCHEMBL8912112 0.83 ALDH1A1 (0.44) SMN1; SMN2MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60260549-A None JP disclosed
EP-4384142-B1 MORDANT-FREE HAIR DYE CONTAINING PLANT DYES HENKEL AG & CO KGAA (DE) 2025-05-07 EP disclosed
EP-3545012-B1 COPOLYMERS AND THEIR USE IN DETERGENT COMPOSITIONS CLARIANT INT LTD (CH) 2025-03-12 EP disclosed
CN-119486725-A (2E) Mixtures and uses of (E) -3- (1, 3-benzodioxol-5-yl) -N-phenyl-N- (tetrahydro-3-furanyl) -2-propenamide 西姆莱斯有限公司 2025-02-18 CN disclosed
EP-3689324-B1 NEW COOLING AGENTS AND PREPARATIONS COMPRISING THEM SYMRISE AG (DE) 2024-11-20 EP disclosed
EP-3801448-B1 WAX DISPERSIONS WITH CONDITIONING PROPERTIES BASF SE (DE) 2024-07-10 EP disclosed
EP-3641564-B1 TASTE MODULATING FLAVORING SUBSTANCES SYMRISE AG (DE) 2024-05-22 EP disclosed
EP-3545066-B1 CLEANING AGENT COMPOSITIONS CONTAINING COPOLYMER CLARIANT INT LTD (CH) 2024-05-01 EP disclosed
US-20240041711-A1 COSMETIC CARE OR FRAGRANCE COMPOSITION IN TWO-PHASE FORM LVMH RECH (FR) 2024-02-08 US disclosed
US-11739072-B2 Heteroaryl compounds and their use MINORYX THERAPEUTICS S.L. (ES) 2023-08-29 US disclosed
EP-0588655-B1 Amidinophenol derivatives ONO PHARMACEUTICAL CO (JP) 1996-12-04 EP disclosed
US-5432178-A Substituted benzoic acid esters; use to prevent or treat inflammatory diseases, allergic diseases, disseminated intravascular coagulation, pancreatitis or multiple organ failure ONO PHARMACEUTICAL CO., LTD. (JP) 1995-07-11 US disclosed
EP-0588655-A1 Amidinophenol derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1994-03-23 EP disclosed
EP-0281177-B1 A SYNTHESIS FOR BETA-LACTAMS WITH THE AID OF A METAL COMPOUND RIJKSUNIVERSITEIT UTRECHT (NL) 1993-09-01 EP disclosed
US-5075043-A Liquid crystals EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0370922-A2 An optical article containing a linear condensation polymer exhibiting a high level of second order polarization susceptibility EASTMAN KODAK COMPANY (US) 1990-05-30 EP disclosed
US-4898955-A INTERMEDIATE FOR PREPARING TRANS-B-LACTAMS GIST-BROCADES N.V. (NL) 1990-02-06 US disclosed
EP-0281177-A1 A synthesis for beta-lactams with the aid of a metal compound RIJKSUNIVERSITEIT UTRECHT (NL) 1988-09-07 EP disclosed
JP-S60260549-A NOVEL SQUARIUM COMPOUND AND PREPARATION THEREOF FUJI XEROX CO LTD 1985-12-23 JP disclosed
US-4310512-A Derivatives of acetic and propionic acids, compositions containing same and use as malodor counteractants BUSH BOAKE ALLEN INC. (US) 1982-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739072-B2 Heteroaryl compounds and their use GBA1, GBA2, GAA SMN1; SMN2 36/4885MEN1 2499/4885KMT2A 2717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.