Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.68 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897329 | 0.77 | HSD11B1 (0.56) | HSD11B1DDB1CRBNCHRNA7POLB | |
| SCHEMBL24167463 | 0.77 | HSD11B1 (0.73) | HSD11B1POLB | |
| SCHEMBL1894852 | 0.76 | HSD11B1 (0.55) | HSD11B1DDB1CRBNCHRNA7POLB | |
| SCHEMBL7358327 | 0.76 | HSD11B1 (0.53) | HSD11B1 | |
| SCHEMBL8022305 | 0.74 | HSD11B1 (0.52) | HSD11B1DDB1CRBNCHRNA7DRD2 | |
| Hydrochloric Acid SCHEMBL27463785 | 0.73 | HSD11B1 (0.51) | HSD11B1DDB1CRBNCHRNA7DRD2 | |
| Cadaverine Tartrate SCHEMBL8034056 | 0.70 | HSD11B1 (0.48) | HSD11B1DDB1CRBNDRD2SLC9A1 | |
| SCHEMBL15744005 | 0.70 | CYP3A4 (0.47) | HSD11B1DDB1CRBNCHRNA7POLB | |
| SCHEMBL23676966 | 0.69 | HTR2C (0.61) | DDB1CRBNDRD2HTR2C | |
| SCHEMBL28829972 | 0.68 | KDM1A (0.60) | HSD11B1DDB1CRBNDRD2SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055665-B1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | PFIZER PROD INC (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1055665-A1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | Pfizer Products Inc. (US) | 2000-11-29 | — | — | EP | disclosed |