Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 7/20 | 0.38 |
| ▸ | CTSL | P07711 | 4/20 | 0.36 |
| ▸ | CTSB | P07858 | 4/20 | 0.36 |
| ▸ | CTSH | P09668 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13971410 | 0.98 | LTA4H (0.41) | ALDH1A1TDP1LTA4HCTSKCTSL | |
| SCHEMBL28808042 | 0.98 | LTA4H (0.41) | ALDH1A1TDP1LTA4HCTSKCTSL | |
| SCHEMBL1716320 | 0.82 | LTA4H (0.44) | ALDH1A1LTA4HCTSKCTSLCTSB | |
| SCHEMBL21008679 | 0.79 | LTA4H (0.56) | LTA4HCTSK | |
| SCHEMBL10021406 | 0.77 | LTA4H (0.38) | ALDH1A1TDP1LTA4HCTSKCTSL | |
| SCHEMBL13610018 | 0.77 | CTSK (0.44) | LTA4HCTSKCTSLCTSBCTSH | |
| SCHEMBL31553 | 0.77 | MAPT (0.37) | ALDH1A1CTSKCTSLCTSBCTSH | |
| SCHEMBL13889050 | 0.74 | CYP2D6 (0.44) | ALDH1A1LTA4HCTSKCTSLCTSB | |
| SCHEMBL3155857 | 0.74 | CYP1A2 (0.40) | LTA4HCTSKCTSLCTSBCTSH | |
| SCHEMBL4226074 | 0.73 | CTSK (0.42) | CTSKCTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |