Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 4/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10866449 | 0.84 | LMNA (0.55) | LMNATSHRLOXL2ALDH1A1CYP2C19 | |
| SCHEMBL1023274 | 0.84 | TSHR (0.57) | LMNATSHRLOXL2ALDH1A1CYP2C19 | |
| SCHEMBL16390246 | 0.81 | TSHR (0.53) | LMNATSHRLOXL2ALDH1A1CYP2C19 | |
| SCHEMBL1625876 | 0.81 | MEN1 (0.56) | LMNATSHRLOXL2ALDH1A1CYP2C19 | |
| SCHEMBL1625885 | 0.81 | MEN1 (0.56) | LMNATSHRLOXL2ALDH1A1CYP2C19 | |
| SCHEMBL10785716 | 0.81 | TSHR (0.53) | LMNATSHRLOXL2ALDH1A1CYP2C19 | |
| SCHEMBL2325845 | 0.81 | LMNA (0.53) | LMNATSHRLOXL2ALDH1A1CYP2C19 | |
| SCHEMBL1625595 | 0.81 | MEN1 (0.56) | LMNATSHRLOXL2ALDH1A1CYP2C19 | |
| SCHEMBL11369488 | 0.81 | LOXL2 (0.57) | LMNATSHRLOXL2ALDH1A1CYP2C19 | |
| SCHEMBL16008875 | 0.81 | TSHR (0.53) | LMNATSHRLOXL2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043308-B1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6353025-B1 | COMPOUNDS AS DRUGS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| EP-1043308-A1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |