Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023261 | 0.94 | ALDH1A1 (0.70) | ALDH1A1NPC1RAB9APDE10AKMT2A | |
| SCHEMBL7011889 | 0.93 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL7022684 | 0.93 | ALDH1A1 (0.73) | ALDH1A1NPC1RAB9APDE10AKMT2A | |
| SCHEMBL7017881 | 0.92 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9APDE10AKMT2A | |
| SCHEMBL7020429 | 0.91 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9APDE10AKMT2A | |
| SCHEMBL7026336 | 0.91 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL7018781 | 0.91 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9APDE10AKMT2A | |
| SCHEMBL7021106 | 0.88 | ALDH1A1 (0.57) | ALDH1A1NPC1RAB9APDE10AKMT2A | |
| SCHEMBL7014792 | 0.88 | ALDH1A1 (0.74) | ALDH1A1NPC1RAB9APDE10AKMT2A | |
| SCHEMBL7098439 | 0.88 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9APDE10AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |