SCHEMBL7103558

SCHEMBL7103558

COc1ccc(/C=C/c2cc(OC)c(/C=C/c3ccc(OC)cc3C#N)cc2OC)c(C#N)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 15/20 0.63
CYP1A1 P04798 14/20 0.63
CYP1B1 Q16678 14/20 0.63
NFE2L2 Q16236 2/20 0.58
CYP3A4 P08684 2/20 0.51
CYP2C19 P33261 2/20 0.51
ALDH1A1 P00352 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CYP2E1 P05181 1/20 0.51
CYP2C8 P10632 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2A6 P11509 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP4B1 P13584 1/20 0.51
CYP2B6 P20813 1/20 0.51
CYP3A5 P20815 1/20 0.51
CYP2A7 P20853 1/20 0.51
CYP3A7 P24462 1/20 0.51
CYP2F1 P24903 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15937803 0.85 NQO1 (0.51) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL15937804 0.85 NQO1 (0.51) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL9239060 0.84 CYP1A1 (0.69) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL9239065 0.84 CYP1A1 (0.69) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL8130457 0.81 CYP1A1 (0.51) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL7103588 0.81 L3MBTL1 (0.46) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL8122560 0.80 CYP1A1 (0.50) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL8124063 0.80 CYP1A1 (0.50) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL8115331 0.80 CYP1A1 (0.50) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4
SCHEMBL8135925 0.80 CYP1A1 (0.50) CYP1A2CYP1A1CYP1B1NFE2L2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004000970-A1 COLOR TUNABLE PHOTOLUMINESCENT BLENDS CASE WESTERN RESERVE UNIVERSITY (US) 2003-12-31 WO disclosed