Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873422 | 0.81 | SPHK1 (0.44) | PLA2G1BPLA2G2ALMNACYP1A2HSD17B10 | |
| SCHEMBL2845490 | 0.78 | SIGMAR1 (0.35) | SIGMAR1LMNANPSR1CHRM2CHRM4 | |
| SCHEMBL29881672 | 0.74 | OPRM1 (0.41) | PLA2G1BPLA2G2ASIGMAR1LMNANPSR1 | |
| SCHEMBL18283422 | 0.74 | OPRM1 (0.41) | PLA2G1BPLA2G2ASIGMAR1LMNANPSR1 | |
| SCHEMBL5787559 | 0.74 | OPRM1 (0.41) | PLA2G1BPLA2G2ASIGMAR1LMNANPSR1 | |
| SCHEMBL8625402 | 0.74 | OPRM1 (0.41) | PLA2G1BPLA2G2ASIGMAR1LMNANPSR1 | |
| SCHEMBL1147313 | 0.72 | PLA2G1B (0.56) | PLA2G1BPLA2G2ASIGMAR1NPSR1 | |
| SCHEMBL7103688 | 0.72 | SIGMAR1 (0.32) | PLA2G1BPLA2G2ASIGMAR1NPSR1CYP1A2 | |
| SCHEMBL23098374 | 0.71 | SIGMAR1 (0.41) | PLA2G1BPLA2G2ASIGMAR1LMNACHRM2 | |
| SCHEMBL417108 | 0.71 | OPRM1 (0.50) | PLA2G1BPLA2G2ASIGMAR1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092737-B1 | Catalyst composition for the production of a polyurethane resin, and method for producing a polyurethane resin | TOSOH CORP (JP) | 2003-09-24 | — | — | EP | disclosed |