Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7771639 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRFFAR3LCKFYN | |
| Hydrogen Peroxide SCHEMBL8626398 | 0.96 | ALDH1A1 (0.50) | ALDH1A1TSHRFFAR3LCKFYN | |
| Acetic Acid SCHEMBL27542231 | 0.92 | FFAR3 (0.58) | ALDH1A1TSHRFFAR3LCKFYN | |
| SCHEMBL25442 | 0.91 | — | — | |
| Benzene SCHEMBL3682238 | 0.88 | ALDH1A1 (0.44) | ALDH1A1TSHRFFAR3LCKFYN | |
| SCHEMBL29877272 | 0.87 | — | — | |
| SCHEMBL30477387 | 0.87 | — | — | |
| Acetone SCHEMBL226043 | 0.87 | LMNA (0.55) | ALDH1A1TSHRFFAR3LCKFYN | |
| SCHEMBL29931207 | 0.87 | — | — | |
| SCHEMBL2991355 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826702-B1 | Latex with two-particle size populations of vinylchloride polymers, manufacturing method thereof and uses | ATOFINA (FR) | 2003-11-12 | — | — | EP | disclosed |
| EP-0826703-B1 | Latex with two-particle size populations of vinylchloride polymers, manufacturing method thereof and use in plastisols | ATOFINA (FR) | 2002-12-04 | — | — | EP | disclosed |
| EP-0826702-A1 | Latex with two-particle size populations of vinylchloride polymers, manufacturing method thereof and uses | ELF ATOCHEM S.A. (FR) | 1998-03-04 | — | — | EP | disclosed |
| EP-0826703-A1 | Latex with two-particle size populations of vinylchloride polymers, manufacturing method thereof and use in plastisols | ELF ATOCHEM S.A. (FR) | 1998-03-04 | — | — | EP | disclosed |