Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRHR | P34981 | 1/20 | 0.36 |
| ▸ | TRHDE | Q9UKU6 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.35 |
| ▸ | ITGAL | P20701 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103890 | 1.00 | NPSR1 (0.36) | NPSR1MEN1KMT2ATRHRTRHDE | |
| SCHEMBL7103872 | 0.89 | TRHR (0.41) | NPSR1MEN1KMT2ATRHRTRHDE | |
| SCHEMBL7103875 | 0.89 | TRHR (0.41) | NPSR1MEN1KMT2ATRHRTRHDE | |
| SCHEMBL7099521 | 0.86 | TRHDE (0.40) | NPSR1MEN1KMT2ATRHRTRHDE | |
| SCHEMBL7099517 | 0.86 | TRHDE (0.40) | NPSR1MEN1KMT2ATRHRTRHDE | |
| SCHEMBL7098260 | 0.86 | TRHR (0.39) | NPSR1MEN1KMT2ATRHRTRHDE | |
| SCHEMBL7098255 | 0.86 | TRHR (0.39) | NPSR1MEN1KMT2ATRHRTRHDE | |
| SCHEMBL7099205 | 0.86 | TRHR (0.48) | NPSR1MEN1KMT2ATRHRTRHDE | |
| SCHEMBL7099203 | 0.86 | TRHR (0.48) | NPSR1MEN1KMT2ATRHRTRHDE | |
| SCHEMBL7099084 | 0.82 | NPSR1 (0.43) | NPSR1MEN1KMT2ATRHRTRHDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | claimed |