Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077444 | 0.99 | ALDH1A1 (0.61) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL11782331 | 0.96 | TSHR (0.59) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL543980 | 0.85 | MEN1 (0.55) | TSHRCYP3A4ALDH1A1LMNAKDM4E | |
| SCHEMBL2237473 | 0.80 | TSHR (0.57) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL28122618 | 0.80 | TSHR (0.66) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL4122426 | 0.80 | TSHR (0.66) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL18526312 | 0.80 | TSHR (0.72) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL2240586 | 0.79 | TSHR (0.58) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL19327371 | 0.79 | ALDH1A1 (0.67) | TSHRMAPK1CYP3A4TP53ALDH1A1 | |
| SCHEMBL4121227 | 0.79 | ALDH1A1 (0.67) | TSHRMAPK1CYP3A4TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1342714-A1 | Process for producing azine compounds and oxime compounds | Daicel Chemical Industries, Ltd. (JP) | 2003-09-10 | — | — | EP | disclosed |
| EP-0233733-A2 | Process for producing N-phthaloyl-p-nitro-L-phenylalanine | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-08-26 | — | — | EP | disclosed |