Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782331 | 0.86 | TSHR (0.59) | MAPTCYP3A4TSHRPDK2ALDH1A1 | |
| Diethyl Phthalate SCHEMBL27518710 | 0.86 | TSHR (0.70) | MEN1KMT2AMAPTCYP1A2USP2 | |
| SCHEMBL7104034 | 0.85 | TSHR (0.60) | CYP3A4TSHRPDK2ALDH1A1HSD17B10 | |
| SCHEMBL27384611 | 0.84 | CDC25B (0.58) | MEN1KMT2AMAPTCYP1A2USP2 | |
| SCHEMBL5077444 | 0.84 | ALDH1A1 (0.61) | MAPTCYP3A4TSHRPDK2ALDH1A1 | |
| SCHEMBL2424940 | 0.83 | KDM4E (0.54) | MEN1KMT2AMAPTCYP1A2USP2 | |
| SCHEMBL6030289 | 0.81 | CASP3 (0.58) | KMT2AMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2823345 | 0.81 | KDM4E (0.47) | MAPK10ALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL28222650 | 0.79 | KDM4E (0.47) | PDK2ALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL2238761 | 0.77 | ALDH1A1 (0.53) | MEN1KMT2AMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294818-A2 | Hindered amine light stabilizers containing aromatic carboxy groups and derivatives | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1988-12-14 | — | — | EP | claimed |
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2023049887-A1 | IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-30 | — | — | WO | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |
| CN-111018664-A | Synthesis method of 2-alkyl-1, 3-propanediol compound | 江苏广域化学有限公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-109476639-A | Pyrrolidin derivatives | 橘生药品工业股份有限公司 | 2019-03-15 | — | — | CN | disclosed |
| EP-3310776-A2 | INHIBITORS OF BRUTON'S TYROSINE KINASE | Pharmacyclics LLC (US) | 2018-04-25 | — | — | EP | disclosed |
| WO-2016196776-A2 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS LLC. (US) | 2016-12-08 | — | — | WO | disclosed |
| WO-2016147132-A1 | A PROCESS FOR THE PREPARATION OF DROXIDOPA | Piramal Enterprises Limited (IN) | 2016-09-22 | — | — | WO | disclosed |
| US-8980837-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-4342765-A | Guanidine derivatives and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-08-03 | — | — | US | disclosed |
| US-4323704-A | ENZYME INHIBITORS USEFUL AGAINST BACTERIA, FUNGUS AND VIRAL INFECTIONS, MALE ANTIFERTILITY AGENTS, IMMUNO-SUPPRESSANTS, AND ANTITUMOR ACTIVITY | MERRELL TORAUDE ET COMPAGNIE (FR) | 1982-04-06 | — | — | US | disclosed |
| EP-0046711-A1 | Fluorinated amino-butyric acid and diaminobutane derivatives | MERRELL TORAUDE ET COMPAGNIE (FR) | 1982-03-03 | — | — | EP | disclosed |
| EP-0046712-A1 | Fluorinated diaminobutane derivatives | MERRELL TORAUDE ET COMPAGNIE (FR) | 1982-03-03 | — | — | EP | disclosed |
| US-4267374-A | BACTERICIDES; VIRICIDES; FUNGICIDES; INHIBITORS OF HYDROLASE ENZYMES; INTERMEDIATE FOR CEPHALOSPORIN COMPOUND | MERRELL TORAUDE ET COMPAGNIE (FR) | 1981-05-12 | — | — | US | disclosed |
| US-4232164-A | Purification of AT-125 | THE UPJOHN COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4225720-A | Purification of AT-125 | THE UPJOHN COMPANY (US) | 1980-09-30 | — | — | US | disclosed |
| EP-0014057-A1 | Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-08-06 | — | — | EP | disclosed |
| US-4139563-A | ENZYME INHIBITORS, ANTIFERTILITY AGENTS, IMMUNOSUPPRESSIVES, ANTITUMOR AGENTS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1979-02-13 | — | — | US | disclosed |
| US-4134918-A | ENZYME INHIBITORS, ANTIBODY INHIBITORS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1979-01-16 | — | — | US | disclosed |