Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.52 |
| ▸ | CDC42BPB | Q9Y5S2 | 3/20 | 0.52 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457181 | 0.80 | KDM1A (0.53) | SLC6A2SLC6A4SLC6A3PRKCZCHRNB2 | |
| SCHEMBL7468564 | 0.80 | KDM1A (0.53) | SLC6A2SLC6A4SLC6A3PRKCZCHRNB2 | |
| SCHEMBL7466333 | 0.80 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3PRKCZCHRNB2 | |
| SCHEMBL7459666 | 0.76 | CHRNB2 (0.67) | SLC6A2SLC6A4SLC6A3PRKCZCHRNB2 | |
| SCHEMBL35429 | 0.76 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3CHRM3TDP1 | |
| SCHEMBL27972144 | 0.76 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3CHRM3TDP1 | |
| SCHEMBL7463964 | 0.75 | CHRNB2 (0.62) | SLC6A2SLC6A4SLC6A3PRKCZCHRNB2 | |
| SCHEMBL21603155 | 0.74 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3PRKCZCHRNB2 | |
| SCHEMBL21604566 | 0.74 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3PRKCZCHRNB2 | |
| SCHEMBL20281548 | 0.74 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3PRKCZCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003500393-A | — | — | 2003-01-07 | — | — | JP | claimed |
| EP-1185513-A2 | ARYL SUBSTITUTED ALKYLAMINES CAPABLE OF ACTIVATING NICOTINIC CHOLINERGIC RECEPTORS | Targacept, Inc. (US) | 2002-03-13 | — | — | EP | claimed |
| WO-2000071520-A2 | ARYL SUBSTITUTED ALKYLAMINES CAPABLE OF ACTIVATING NICOTINIC CHOLINERGIC RECEPTORS | TARGACEPT, INC. (US) | 2000-11-30 | — | — | WO | claimed |