Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106248 | 0.69 | NOS1 (0.32) | — | |
| SCHEMBL4169706 | 0.68 | SLC18A3 (0.42) | ADRA1A | |
| SCHEMBL10509508 | 0.67 | MAPT (0.38) | — | |
| Hydrochloric Acid SCHEMBL6997190 | 0.66 | SLC18A3 (0.41) | ADRA1A | |
| SCHEMBL22506964 | 0.64 | HTR2C (0.35) | — | |
| SCHEMBL10495281 | 0.63 | F2 (0.55) | — | |
| SCHEMBL752611 | 0.61 | F2 (0.48) | — | |
| Hydrochloric Acid SCHEMBL29008442 | 0.61 | BLM (0.57) | — | |
| Hydrochloric Acid SCHEMBL28555632 | 0.61 | BLM (0.57) | — | |
| SCHEMBL23978106 | 0.60 | HTR2C (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278732-A1 | 1-AROYL-PIPERIDINYL BENZAMIDINES | Aventis Pharmaceuticals Inc. (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001081310-A1 | 1-AROYL-PIPERIDINYL BENZAMIDINES | AVENTIS PHARMACEUTICALS INC. (US) | 2001-11-01 | — | — | WO | disclosed |