Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.63 |
| ▸ | RELA | Q04206 | 2/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28196453 | 0.86 | NPC1 (0.59) | NPC1MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL4954320 | 0.85 | NPC1 (0.81) | NPC1MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL18774822 | 0.85 | NPC1 (0.54) | NPC1MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL28165865 | 0.84 | MAPT (0.61) | NPC1MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL10225874 | 0.82 | SMN1; SMN2 (0.68) | NPC1MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL29386544 | 0.82 | SMN1; SMN2 (0.68) | NPC1MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL13170666 | 0.81 | NPC1 (0.56) | NPC1MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL28860564 | 0.81 | MAPK1 (0.54) | NPC1MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL5219136 | 0.80 | NPC1 (0.50) | NPC1MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL9453978 | 0.80 | NPC1 (0.68) | NPC1MAPTKDM4ERAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3931184-A1 | METHOD FOR PRODUCING QUINOXALINES | Technische Universität Wien (AT) | 2022-01-05 | — | — | EP | claimed |
| US-5360688-A | Composite black and white substrate for color proofing films | HOECHST CELANESE CORPORATION (US) | 1994-11-01 | — | — | US | claimed |
| CN-117050324-A | Quinoxaline bridged terpyridine iron coordination polymer electrochromic material | 南京林业大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-113774411-B | Method for electrochemically synthesizing aryl-substituted quinoxaline (ketone) derivative | 浙江工业大学 | 2022-12-27 | — | — | CN | disclosed |
| EP-3931184-A1 | METHOD FOR PRODUCING QUINOXALINES | Technische Universität Wien (AT) | 2022-01-05 | — | — | EP | disclosed |
| CN-111116496-B | Synthetic method of quinoxaline heterocyclic derivative | 扬州大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-108530423-B | Water-soluble aggregation-induced emission quinoxaline compound and preparation method and application thereof | 华南理工大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-111116496-A | Synthetic method of quinoxaline heterocyclic derivative | 扬州大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-108530423-A | A kind of water solubility aggregation-induced emission quinoxaline compounds and the preparation method and application thereof | 华南理工大学 | 2018-09-14 | — | — | CN | disclosed |
| CN-105294776-B | A kind of preparation method of the symmetrical dimer of nitrogen heterocyclic ring aromatic compound | 兰州大学 | 2018-06-15 | — | — | CN | disclosed |
| CN-105439965-B | The synthetic method of quinoxaline heterocycle and its derivative | 江苏恒安化工有限公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-106414414-A | Method for manufacturing triketone compound | 庵原化学工业株式会社 | 2017-02-15 | — | — | CN | disclosed |
| US-8124625-B2 | enhancing the expression of apoAI; prevention or therapy of dislipidemia | SHIONOGI & CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-8053445-B2 | Utilities of olefin derivatives | SHIONOGI & CO., LTD. (JP) | 2011-11-08 | — | — | US | disclosed |
| US-20090036457-A1 | Utilities of olefin derivatives | YAMAMORI TERUO | 2009-02-05 | — | — | US | disclosed |
| US-20040242615-A1 | Utilities of olefin derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| US-5294515-A | Multicolor lithographic proofing image | HOECHST CELANESE CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| CN-1038525-A | The colour filter system of LCD | HOECHST CELANESE CORP (US) | 1990-01-03 | — | — | CN | disclosed |
| US-4737445-A | 2,3-DIHYDRO-1H-CYCLOPENTA(B)QUINOLINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242615-A1 | Utilities of olefin derivatives | APOL1, NR1H2, APOB | NPC1 19/4885MAPT 3896/4885KDM4E 4415/4885 |
| US-20090036457-A1 | Utilities of olefin derivatives | APOL1, APOB, NR1H2 | NPC1 48/4885MAPT 3909/4885KDM4E 4647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.