Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104539 | 1.00 | CTSK (0.44) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7105576 | 0.83 | CTSK (0.43) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7105585 | 0.83 | CTSK (0.43) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2577312 | 0.78 | CTSK (0.53) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL18614255 | 0.76 | CTSK (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7273189 | 0.76 | CTSK (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL3448016 | 0.76 | CTSK (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9763696 | 0.75 | CTSK (0.46) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9763693 | 0.75 | CTSK (0.46) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7105936 | 0.74 | TSHR (0.55) | CTSKCTSSCYP2D6PPARAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990640-B1 | Beta-Hydroxyaspartic acid derivatives | SUNTORY LTD (JP) | 2003-01-22 | — | — | EP | disclosed |
| EP-0844234-B1 | Beta-hydroxyaspartic acid derivatives | SUNTORY LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6147113-A | ADMINISTERING TO TREAT NERVOUS SYSTEM AND BRAIN DISORDERS; GLUTAMATE UPTAKE INHIBITORS | SUNTORY LIMITED (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0990640-A2 | Beta-Hydroxyaspartic acid derivatives | SUNTORY LIMITED (JP) | 2000-04-05 | — | — | EP | disclosed |
| EP-0948962-A2 | Beta-hydroxyaspartic acid derivatives | SUNTORY LIMITED (JP) | 1999-10-13 | — | — | EP | disclosed |