Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4539745 | 0.99 | TYMS (0.52) | TYMSDHFR | |
| SCHEMBL16807869 | 0.79 | TYMS (0.61) | TYMSDHFR | |
| Nolatrexed SCHEMBL710461 | 0.69 | TYMS (1.00) | TYMSDHFR | |
| SCHEMBL7826662 | 0.68 | TYMS (1.00) | TYMS | |
| Nolatrexed SCHEMBL316632 | 0.68 | TYMS (0.97) | TYMSDHFR | |
| Nolatrexed SCHEMBL27935384 | 0.68 | TYMS (0.97) | TYMSDHFR | |
| Nolatrexed SCHEMBL29420099 | 0.68 | TYMS (0.97) | TYMSDHFR | |
| Nolatrexed SCHEMBL18489 | 0.64 | TYMS (0.66) | TYMSDHFR | |
| SCHEMBL28069299 | 0.60 | TYMS (0.45) | TYMSDHFR | |
| SCHEMBL24072199 | 0.59 | PARP1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253106-B2 | Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells | EISAI, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-20170184603-A1 | Monoclonal Antibodies That Specifically Block Biological Activity Of A Tumor Antigen | EISAI INC. | 2017-06-29 | — | — | US | disclosed |
| US-9650440-B2 | Monoclonal antibodies that specifically block biological activity of a tumor antigen | MORPHOTEK, INC. (US) | 2017-05-16 | — | — | US | disclosed |
| US-9624297-B2 | Monoclonal antibodies that specifically block biological activity of a tumor antigen | MORPHOTEK, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-20170073425-A1 | Antibodies With Immune Effector Activity and That Internalize In Folate Receptor Alpha-Positive Cells | EISAI INC. | 2017-03-16 | — | — | US | disclosed |
| US-9522195-B2 | Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells | MORPHOTEK, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| EP-3101034-A1 | MONOCLONAL ANTIBODIES THAT SPECIFICALLY BIND TO FOLATE RECEPTOR ALPHA | Morphotek, Inc. (US) | 2016-12-07 | — | — | EP | disclosed |
| US-20160058885-A1 | Antibodies With Immune Effector Activity and that Internalize In Folate Receptor Alpha-positive Cells | EISAI INC. | 2016-03-03 | — | — | US | disclosed |
| US-9144614-B2 | Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells | MORPHOTEK, INC. (US) | 2015-09-29 | — | — | US | disclosed |
| US-20130189272-A1 | Monoclonal Antibodies That Specifically Block Biological Activity Of A Tumor Antigen | MORPHOTEK, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| EP-2172487-A1 | Antibodies with Immune Effector Activity that Internalize in Folate Receptor Alpha-Positive Cells | Morphotek Inc. (US) | 2010-04-07 | — | — | EP | disclosed |
| US-20090324594-A1 | Antibodies With Immune Effector Activity And That Internalize In Folate Receptor Alpha-Positive Cells | EISAI INC. | 2009-12-31 | — | — | US | disclosed |
| US-20090274697-A1 | Monoclonal Antibodies That Specifically Block Biological Activity Of A Tumor Antigen | EISAI INC. | 2009-11-05 | — | — | US | disclosed |
| EP-1879922-A2 | ANTIBODIES WITH IMMUNE EFFECTOR ACTIVITY AND THAT INTERNALIZE IN FOLATE RECEPTOR ALPHA-POSITIVE CELLS | Morphotek, Inc. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006116592-A9 | ANTIBODIES WITH IMMUNE EFFECTOR ACTIVITY AND THAT INTERNALIZE IN FOLATE RECEPTOR ALPHA-POSITIVE CELLS | MORPHOTEK INC (US) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006116592-A2 | ANTIBODIES WITH IMMUNE EFFECTOR ACTIVITY AND THAT INTERNALIZE IN FOLATE RECEPTOR ALPHA-POSITIVE CELLS | MORPHOTEK, INC. (US) | 2006-11-02 | — | — | WO | disclosed |
| EP-1716179-A2 | MONOCLONAL ANTIBODIES THAT SPECIFICALLY BIND TO FOLATE RECEPTOR ALPHA | Morphotek, Inc. (US) | 2006-11-02 | — | — | EP | disclosed |
| US-20060239910-A1 | Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells | MORPHOTEK INC. | 2006-10-26 | — | — | US | disclosed |
| US-20050232919-A1 | Monoclonal antibodies that specifically block biological activity of a tumor antigen | MORPHOTEK, INC. (US) | 2005-10-20 | — | — | US | disclosed |
| WO-2005080431-A2 | MONOCLONAL ANTIBODIES THAT SPECIFICALLY BIND TO FOLATE RECEPTOR ALPHA | MORPHOTEK, INC. (US) | 2005-09-01 | — | — | WO | disclosed |