Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL708758 | 0.85 | EGLN2 (0.45) | SMN1; SMN2EGLN2ALDH1A1KDM4ERCE1 | |
| SCHEMBL710043 | 0.77 | MBOAT4 (0.41) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL11468935 | 0.72 | KDM4E (0.56) | SMN1; SMN2EGLN2ALDH1A1KDM4ERCE1 | |
| SCHEMBL11484815 | 0.66 | ALDH1A1 (0.54) | SMN1; SMN2EGLN2ALDH1A1KDM4ERCE1 | |
| SCHEMBL710035 | 0.66 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL710462 | 0.65 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL709421 | 0.65 | KDM4E (0.51) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL710046 | 0.64 | PDE2A (0.39) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL710042 | 0.63 | PDE2A (0.42) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3378140 | 0.62 | MBOAT4 (0.43) | SMN1; SMN2ALDH1A1KDM4EGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118113-B1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA (JP) | 2013-01-30 | — | — | EP | disclosed |
| US-8124760-B2 | Pyridyl-triazolopyrimidine derivative or its salt, pesticide containing it and its production process | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20100087452-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD (JP) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087452-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | SCN5A, CHRNA5, NR5A2 | SMN1; SMN2 3356/4885EGLN2 4182/4885ALDH1A1 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.