Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103975 | 0.96 | S1PR1 (0.34) | S1PR1S1PR5PTGS2 | |
| SCHEMBL7105433 | 0.92 | S1PR1 (0.35) | S1PR1S1PR5PTGS2 | |
| SCHEMBL7106836 | 0.87 | S1PR1 (0.36) | S1PR1S1PR5PTGS2 | |
| SCHEMBL7189489 | 0.86 | SPHK1 (0.34) | SPHK1S1PR1S1PR5SPHK2PTGS2 | |
| SCHEMBL27757695 | 0.85 | SPHK1 (0.37) | SPHK1S1PR1S1PR5SPHK2PTGS2 | |
| SCHEMBL7109462 | 0.84 | GCGR (0.31) | — | |
| SCHEMBL7109434 | 0.84 | SLC6A2 (0.37) | PTGS2 | |
| Hydrochloric Acid SCHEMBL27670364 | 0.84 | SPHK1 (0.36) | SPHK1S1PR1S1PR5SPHK2PTGS2 | |
| SCHEMBL7110770 | 0.83 | HSD11B1 (0.34) | PTGS2 | |
| SCHEMBL7108905 | 0.83 | SLC6A2 (0.37) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |