Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111534 | 0.99 | SLC6A2 (0.37) | SLC6A2SLC6A4HSD11B1HTR2AHTR2C | |
| SCHEMBL7108905 | 0.99 | SLC6A2 (0.37) | SLC6A2SLC6A4HSD11B1HTR2AHTR2C | |
| SCHEMBL7108748 | 0.97 | SLC6A2 (0.37) | SLC6A2SLC6A4HSD11B1HTR2AHTR2C | |
| SCHEMBL7110770 | 0.97 | HSD11B1 (0.34) | SLC6A2SLC6A4HSD11B1HTR2AHTR2C | |
| SCHEMBL7106922 | 0.95 | HSD11B1 (0.34) | SLC6A2SLC6A4HSD11B1HTR2AHTR2C | |
| SCHEMBL7111659 | 0.94 | DRD2 (0.34) | SLC6A2SLC6A4HSD11B1HTR2AHTR2C | |
| SCHEMBL7103915 | 0.92 | HSD11B1 (0.33) | SLC6A2SLC6A4HSD11B1HTR2AHTR2C | |
| SCHEMBL7109568 | 0.92 | TLR8 (0.31) | HSD11B1RARBTLR8 | |
| SCHEMBL7109462 | 0.91 | GCGR (0.31) | SLC6A2SLC6A4HSD11B1HTR2AHTR2C | |
| SCHEMBL7105397 | 0.89 | EDNRB (0.32) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |