Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041180 | 0.88 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL7038210 | 0.84 | — | — | |
| SCHEMBL7040750 | 0.81 | GRIN2B (0.53) | CCR1 | |
| SCHEMBL8829509 | 0.78 | DPP4 (0.49) | SLC6A4 | |
| SCHEMBL7107899 | 0.76 | HTR1D (0.54) | SLC6A4 | |
| SCHEMBL7110814 | 0.75 | SLC6A4 (0.57) | SLC6A4 | |
| SCHEMBL7307698 | 0.74 | HTR1D (0.53) | — | |
| SCHEMBL7038215 | 0.73 | HTR1D (0.54) | — | |
| SCHEMBL7304581 | 0.73 | CCR1 (0.48) | CCR1 | |
| SCHEMBL9036819 | 0.73 | HTR1D (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387593-A | Anxiolytic agents | BRISTON-MYERS SQUIBB (US) | 1995-02-07 | — | — | US | claimed |
| EP-1037637-B1 | USE OF 5HT1A RECEPTOR ANTAGONISTS FOR PREVENTING AND/OR TREATING TEMPORAL LOBE EPILEPSY | UNIV PRINCETON (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1037637-A1 | USE OF 5HT1A RECEPTOR ANTAGONISTS FOR PREVENTING AND/OR TREATING TEMPORAL LOBE EPILEPSY | PRINCETON UNIVERSITY (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999029323-A1 | USE OF 5HT1A RECEPTOR ANTAGONISTS FOR PREVENTING AND/OR TREATING TEMPORAL LOBE EPILEPSY | PRINCETON UNIVERSITY (US) | 1999-06-17 | — | — | WO | disclosed |
| EP-0546583-B1 | Piperazinyl-and piperidinyl-cyclohexanols | BRISTOL MYERS SQUIBB CO (US) | 1996-05-22 | — | — | EP | disclosed |
| US-5478828-A | Anxiolytic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-12-26 | — | — | US | disclosed |
| US-5387593-A | Anxiolytic agents | BRISTON-MYERS SQUIBB (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0546583-A1 | Piperazinyl-and piperidinyl-cyclohexanols | Bristol-Myers Squibb Company (US) | 1993-06-16 | — | — | EP | disclosed |