Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 15/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665657 | 0.93 | ESR1 (0.86) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL15660902 | 0.92 | ESR1 (0.85) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL25079639 | 0.89 | ESR1 (0.81) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL8630381 | 0.89 | ESR1 (0.80) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL26158897 | 0.88 | ESR1 (0.79) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL8628025 | 0.86 | ESR1 (0.76) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL8562371 | 0.86 | ESR1 (0.76) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL8626952 | 0.86 | ESR1 (0.80) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL31683627 | 0.86 | ESR1 (0.81) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL8631942 | 0.86 | ESR1 (0.81) | ESR1ESR2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819686-B1 | Benzothiophene compounds, and uses and formulations thereof | LILLY CO ELI (US) | 2003-10-01 | — | — | EP | disclosed |
| US-5780648-A | Benzothiophene compounds, and uses formulations thereof | ELI LILLY AND COMPANY (US) | 1998-07-14 | — | — | US | disclosed |
| EP-0819686-A1 | Benzothiophene compounds, and uses and formulations thereof | ELI LILLY AND COMPANY (US) | 1998-01-21 | — | — | EP | disclosed |