Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.76 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625838 | 0.94 | ESR1 (0.65) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL8630381 | 0.93 | ESR1 (0.80) | ESR1ESR2CNR1MEN1PLD2 | |
| SCHEMBL7075690 | 0.89 | TUBB4A (0.60) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL11547223 | 0.88 | ESR1 (0.63) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL7104864 | 0.86 | ESR1 (1.00) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL19308140 | 0.85 | ESR1 (0.73) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL7075680 | 0.84 | CNR1 (0.69) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL7080421 | 0.84 | ESR1 (0.69) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL11548512 | 0.83 | CNR1 (0.71) | ESR1ESR2CNR1CNR2TDP1 | |
| SCHEMBL7148725 | 0.83 | CNR1 (0.70) | ESR1ESR2TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780648-A | Benzothiophene compounds, and uses formulations thereof | ELI LILLY AND COMPANY (US) | 1998-07-14 | — | — | US | disclosed |