Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10343478 | 0.98 | TSHR (0.39) | TSHRTP53TDP1ACHEALDH1A1 | |
| Dimethylamine SCHEMBL10692608 | 0.94 | TSHR (0.36) | TSHRTP53TDP1ACHE | |
| SCHEMBL11695523 | 0.87 | TSHR (0.37) | TSHRTP53TDP1ALDH1A1CYP3A4 | |
| SCHEMBL11124791 | 0.85 | TSHR (0.36) | TSHRCYP3A4 | |
| SCHEMBL482316 | 0.84 | MEN1 (0.34) | CYP3A4MEN1KMT2A | |
| SCHEMBL11694816 | 0.84 | LPAR3 (0.38) | TSHRCYP3A4 | |
| SCHEMBL11699342 | 0.84 | LPAR3 (0.38) | TSHRCYP3A4 | |
| Ammonia Solution, Strong SCHEMBL10929931 | 0.83 | MEN1 (0.33) | CYP3A4MEN1KMT2A | |
| SCHEMBL11703484 | 0.83 | MEN1 (0.33) | CYP3A4MEN1KMT2A | |
| SCHEMBL11135623 | 0.83 | MEN1 (0.33) | CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110440-A | ARTHROPODICIDE, NEMATOCIDE | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1978-08-29 | — | — | US | claimed |
| JP-62039595-A | — | — | None | — | — | JP | disclosed |
| JP-56138104-A | — | — | None | — | — | JP | disclosed |
| JP-56138103-A | — | — | None | — | — | JP | disclosed |
| US-20030087958-A1 | Hydrazine oxoacetamide derivative and insecticide | AGRO-KANESHO CO., LTD. (JP) | 2003-05-08 | — | — | US | disclosed |
| US-6399542-B1 | INSECTICIDES; PESTICIDES | AGRO-KANESHO CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| US-6399659-B2 | EFFECTIVE AT LOW CONCENTRATIONS | AGRO-KANESHO CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| US-20010044464-A1 | Hydrazine oxoacetamide derivative and insecticide | AGRO-KANESHO CO., LTD. (JP) | 2001-11-22 | — | — | US | disclosed |
| US-6291399-B1 | Agent for controlling diseases and insect pests, containing alkoxyimino-substituted bicyclic derivative as active ingredient | AGRO-KANESHO CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1123920-A1 | HYDRAZINOOXOACETAMIDE DERIVATIVES AND INSECTICIDE | Agro-Kanesho Co. Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-4268506-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (US) | 1981-05-19 | — | — | US | disclosed |
| US-4248866-A | Combating arthropods with N-(O-ethyl-S-n-propyl-thiophosphoryloxy)-naphthalimides | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-03 | — | — | US | disclosed |
| US-4192829-A | INSECTICIDES, MITICIDES, NEMATOCIDES | EXXON RESEARCH & ENGINEERING CO. (US) | 1980-03-11 | — | — | US | disclosed |
| US-4139615-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |
| US-4110440-A | ARTHROPODICIDE, NEMATOCIDE | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1978-08-29 | — | — | US | disclosed |
| US-4075332-A | Pesticidal O,S'-dialkyl S-hydrocarbylthioalkyl dithiophosphates and oxidized derivatives thereof | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-02-21 | — | — | US | disclosed |
| US-4028377-A | PESTICIDES, INSECTICIDES, MITICIDES | CIBA-GEIGY CORPORATION (US) | 1977-06-07 | — | — | US | disclosed |
| US-3948940-A | Pesticidal phthalimido phosphorous ester compounds | CIBA-GEIGY CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |
| US-3934011-A | Combating insects and acarids with S-diphenylmethyl-dithiophosphates | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933947-A | INSECTICIDE, MITICIDE, NEMATOCIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087958-A1 | Hydrazine oxoacetamide derivative and insecticide | DDT, CYP2E1, HCN1 | TSHR 2764/4885TP53 3739/4885TDP1 4269/4885 |
| US-20010044464-A1 | Hydrazine oxoacetamide derivative and insecticide | DDT, CYP2E1, HCN1 | TSHR 2764/4885TP53 3739/4885TDP1 4269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.