Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 8/20 | 0.41 |
| ▸ | THRA | P10827 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365593 | 0.80 | MEN1 (0.47) | MEN1KMT2AKDM4EPOLBPRNP | |
| SCHEMBL20339735 | 0.80 | RXRA (0.46) | MEN1KMT2AKDM4EPOLBPRNP | |
| SCHEMBL14818819 | 0.80 | AKT1 (0.55) | ALDH5A1ABATAKT1THRBTHRA | |
| SCHEMBL7032910 | 0.76 | MEN1 (0.44) | MEN1KMT2AKDM4EPOLBPRNP | |
| SCHEMBL30957376 | 0.74 | MEN1 (0.66) | MEN1KMT2AKDM4EPOLBPRNP | |
| SCHEMBL27612958 | 0.74 | KMT2A (0.41) | MEN1KMT2AKDM4EPOLBPRNP | |
| SCHEMBL27357797 | 0.74 | SMN1; SMN2 (0.50) | MEN1KMT2AKDM4EPOLBPRNP | |
| Maleic Acid SCHEMBL27357801 | 0.74 | KMT2A (0.53) | THRBMEN1KMT2AKDM4EPOLB | |
| SCHEMBL2666244 | 0.74 | MEN1 (0.59) | MEN1KMT2AKDM4EPOLBPRNP | |
| SCHEMBL6847816 | 0.73 | CYP2A6 (0.42) | MEN1KMT2AKDM4EPOLBPRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343798-A1 | 6-O-CARBAMOYL KETOLIDE DERIVATIVES OF ERYTHROMYCIN USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002046204-A1 | 6-0-CARBAMOYL KETOLIDE DERIVATIVES OF ERYTHROMYCIN USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-06-13 | — | — | WO | disclosed |