Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850714 | 0.84 | MEN1 (0.38) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL6850708 | 0.84 | MEN1 (0.38) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL27594296 | 0.78 | MEN1 (0.40) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL8363956 | 0.77 | KMT2A (0.56) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL30957376 | 0.77 | MEN1 (0.66) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL2666244 | 0.76 | MEN1 (0.59) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL8365593 | 0.76 | MEN1 (0.47) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL20339735 | 0.76 | RXRA (0.46) | KMT2AMEN1RAB9APOLBKDM4E | |
| SCHEMBL7032910 | 0.74 | MEN1 (0.44) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL7104926 | 0.74 | ALDH5A1 (0.44) | KMT2AMEN1NPC1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |