Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 16/20 | 0.77 |
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | NSD2 | O96028 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7104925 | 1.00 | INSR (0.77) | INSRAPPMAPTKMT2ATHRB | |
| SCHEMBL6128353 | 0.99 | INSR (0.79) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL38659057 | 0.89 | INSR (0.79) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL29757617 | 0.89 | INSR (0.97) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL7028400 | 0.89 | INSR (0.97) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL5679445 | 0.89 | INSR (0.97) | INSRAPPMAPTKMT2ATHRB | |
| SCHEMBL9580682 | 0.87 | INSR (1.00) | INSRAPPMAPTKMT2ATHRB | |
| SCHEMBL9580683 | 0.87 | INSR (1.00) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL8390009 | 0.86 | INSR (0.98) | INSRAPP | |
| Iodide SCHEMBL8390007 | 0.86 | INSR (0.98) | INSRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672953-B1 | Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium | TOPPAN PRINTING CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-6045953-A | COMPRISES A SUBSTRATE, A PHOTOSENSITIVE LAYER FORMED ON THE SUBSTRATE BY COATING A PHOTOSENSITIVE SOLUTION CONTAINING AN ALICYCLIC, SOLVENT SOLUBLE, CATIONIC POLYMERIZABLE EPOXY RESIN AND AN ACRYLATE POLYMER | TOPPAN PRINTING CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0697631-B1 | Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium | TOPPAN PRINTING CO LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5698345-A | CATIONIC POLYMERIZATION OF THERMOSETTING EPOXY OLIGOMER | TOPPAN PRINTING CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0697631-A1 | Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium | Toppan Printing Co., Ltd. (JP) | 1996-02-21 | — | — | EP | disclosed |
| EP-0672953-A2 | Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium | Toppan Printing Co., Ltd. (JP) | 1995-09-20 | — | — | EP | disclosed |