SCHEMBL710514

SCHEMBL710514

C#CCOC(=O)CCC(=O)OCCOC(=O)C(=C)C

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
TSHR P16473 5/20 0.42
GSTP1 P09211 1/20 0.42
ALDH1A1 P00352 3/20 0.40
TAAR1 Q96RJ0 1/20 0.40
MAPT P10636 1/20 0.39
BLM P54132 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA1A P35348 1/20 0.36
DGKA P23743 1/20 0.34
NPC1 O15118 1/20 0.32
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16744077 0.86 THRB (0.61) THRBTSHRALDH1A1MAPTBLM
SCHEMBL124287 0.86 THRB (0.61) THRBTSHRALDH1A1MAPTBLM
SCHEMBL8731559 0.83 THRB (0.50) THRBTSHRGSTP1ALDH1A1POLB
SCHEMBL15249368 0.82 THRB (0.53) THRBTSHRALDH1A1MAPTBLM
SCHEMBL194435 0.82
SCHEMBL5071449 0.81 THRB (0.49) THRBTSHRGSTP1ALDH1A1POLB
SCHEMBL1478120 0.80 THRB (0.55) THRBTSHRALDH1A1MAPTBLM
SCHEMBL28959481 0.80 THRB (0.66) THRBTSHRALDH1A1MAPTBLM
SCHEMBL2466488 0.80 THRB (0.59) THRBTSHRALDH1A1MAPTBLM
SCHEMBL22258182 0.79 THRB (0.53) THRBTSHRALDH1A1MAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8795782-B2 Polymeric coatings and methods for forming them COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2014-08-05 US disclosed
US-20120178165-A1 POLYMERIC COATINGS AND METHODS FOR FORMING THEM COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2012-07-12 US disclosed
US-8124188-B2 Polymeric coatings and methods for forming them COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2012-02-28 US disclosed
EP-2052045-A1 POLYMERIC COATINGS AND METHODS FOR FORMING THEM Commonwealth Scientific and Industrial Research Organisation (AU) 2009-04-29 EP disclosed
WO-2008019450-A1 POLYMERIC COATINGS AND METHODS FOR FORMING THEM COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-02-21 WO disclosed
US-20080045686-A1 POLYMERIC COATINGS AND METHODS FOR FORMING THEM COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-02-21 US disclosed