SCHEMBL7105404

SCHEMBL7105404

Cc1cc(-c2c(C)c(O)c(C)c(-c3ccc(O)c(C)c3)c2C)ccc1O

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ HSD17B1 P14061 6/20 0.48
▸ HSD17B2 P37059 6/20 0.48
▸ ESR2 Q92731 5/20 0.47
▸ TP53 P04637 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ PDE10A Q9Y233 1/20 0.43
▸ CYP3A4 P08684 1/20 0.42
▸ CYP2D6 P10635 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ ESR1 P03372 5/20 0.42
▸ AR P10275 3/20 0.41
▸ FGFR1 P11362 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ TLR8 Q9NR97 1/20 0.40
▸ SENP1 Q9P0U3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17753418 0.90 HSD17B1 (0.47) HSD17B1HSD17B2ESR2TP53TDP1
SCHEMBL6701966 0.89 HSD17B1 (0.50) HSD17B1HSD17B2ESR2TP53TDP1
SCHEMBL6699314 0.89 HSD17B1 (0.53) HSD17B1HSD17B2ESR2TP53TDP1
SCHEMBL26979937 0.79 HSD17B1 (0.68) HSD17B1HSD17B2ESR2TP53TDP1
SCHEMBL29696046 0.79 HSD17B1 (0.68) HSD17B1HSD17B2ESR2TP53TDP1
SCHEMBL272034 0.79 HSD17B1 (0.68) HSD17B1HSD17B2ESR2TP53TDP1
SCHEMBL29429121 0.79 HSD17B1 (0.68) HSD17B1HSD17B2ESR2TP53TDP1
SCHEMBL8417989 0.77 HSD17B1 (0.43) HSD17B1HSD17B2ESR2TP53TDP1
Hydrogen Sulfide SCHEMBL6269773 0.77 HSD17B1 (0.65) HSD17B1HSD17B2ESR2TP53TDP1
Hydrogen Sulfide SCHEMBL22042810 0.77 HSD17B1 (0.65) HSD17B1HSD17B2ESR2TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943957-B1 Thermographic imaging element EASTMAN KODAK CO (US) 2003-09-17 — — EP disclosed
EP-0677775-B1 Thermal transfer imaging process AGFA GEVAERT (BE) 2002-06-12 — — EP disclosed
US-6312885-B1 WITH IMAGE FORMING LAYERS OF DIFFERENT THERMAL EXPANSION COEFFICIENTS FUJI PHOTO FILM CO., LTD. (JP) 2001-11-06 — — US disclosed
EP-0671283-B1 Thermal transfer imaging process AGFA GEVAERT NV (BE) 2001-07-04 — — EP disclosed
EP-0678775-B1 Thermal transfer process AGFA GEVAERT NV (BE) 2001-06-06 — — EP disclosed
EP-0943960-B1 Thermographic imaging element EASTMAN KODAK CO (US) 2001-05-30 — — EP disclosed
EP-0943959-B1 Thermographic imaging element EASTMAN KODAK CO (US) 2001-05-30 — — EP disclosed
EP-0943958-B1 Thermographic imaging element EASTMAN KODAK CO (US) 2001-05-23 — — EP disclosed
EP-0713133-B1 Receiving element for use in thermal transfer printing AGFA GEVAERT NV (BE) 2001-05-16 — — EP disclosed
EP-0706080-B1 Thermal transfer printing of a reducing agent to a silver source contained in an image receiving layer AGFA GEVAERT NV (BE) 2001-03-07 — — EP disclosed
EP-0678775-A1 Thermal transfer process AGFA-GEVAERT N.V. (BE) 1995-10-25 — — EP disclosed
US-5460938-A Containing a halogenated, sulfone-containing quinoline compound as antifogging agent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-10-24 — — US disclosed
EP-0677775-A1 Thermal transfer imaging process AGFA-GEVAERT N.V. (BE) 1995-10-18 — — EP disclosed
EP-0674216-A1 Thermal transfer imaging process and donor element for use therein AGFA-GEVAERT N.V. (BE) 1995-09-27 — — EP disclosed
EP-0671283-A1 Thermal transfer imaging process AGFA-GEVAERT N.V. (BE) 1995-09-13 — — EP disclosed
US-5432287-A Antifoggants MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-07-11 — — US disclosed
US-5393654-A Heptamethine cyanine dyes in which both nitrogen atoms of the cyanine chromophore bear a carboxyalkyl substituent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-28 — — US disclosed
US-5387498-A Exposure to actinic radiation causes production of acidic species in exposed regions which inhibit reduction of silver source MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-07 — — US disclosed
US-5374514-A Photographic silver halide, reducible silver source, reducing agent, binder, specific antifoggant and/or image stabilizer CARESTREAM DENTAL LLC 1994-12-20 — — US disclosed
EP-0537975-A1 Positive-acting photothermographic materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-04-21 — — EP disclosed
Send feedback