Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105470 | 1.00 | NR1H4 (0.47) | NR1H4KMT2AMEN1NPSR1ITGA4 | |
| SCHEMBL7100744 | 0.90 | ITGA4 (0.51) | KMT2AMEN1NPSR1ITGA4ITGB1 | |
| SCHEMBL7100747 | 0.90 | ITGA4 (0.51) | KMT2AMEN1NPSR1ITGA4ITGB1 | |
| SCHEMBL7099187 | 0.90 | ITGA4 (0.49) | NR1H4KMT2AMEN1NPSR1ITGA4 | |
| SCHEMBL7099189 | 0.90 | ITGA4 (0.49) | NR1H4KMT2AMEN1NPSR1ITGA4 | |
| SCHEMBL7102251 | 0.88 | ITGB1 (0.46) | KMT2AMEN1NPSR1ITGA4ITGB1 | |
| SCHEMBL7102248 | 0.88 | ITGB1 (0.46) | KMT2AMEN1NPSR1ITGA4ITGB1 | |
| SCHEMBL7097645 | 0.87 | MME (0.49) | KMT2AMEN1NPSR1 | |
| SCHEMBL7098080 | 0.87 | FPR2 (0.46) | KMT2AMEN1NPSR1ITGA4ITGB1 | |
| SCHEMBL7098083 | 0.87 | FPR2 (0.46) | KMT2AMEN1NPSR1ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | claimed |