Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.47 |
| ▸ | CTSS | P25774 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106002 | 1.00 | CTSK (0.47) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL2577312 | 0.88 | CTSK (0.53) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9782230 | 0.87 | CTSK (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL5024361 | 0.87 | CTSK (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL999110 | 0.85 | CTSK (0.51) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL1312767 | 0.85 | CTSK (0.51) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL1311851 | 0.85 | CTSK (0.51) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL708582 | 0.85 | CTSK (0.51) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL16710007 | 0.85 | CTSK (0.51) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL1312765 | 0.85 | CTSK (0.51) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990640-B1 | Beta-Hydroxyaspartic acid derivatives | SUNTORY LTD (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6147113-A | ADMINISTERING TO TREAT NERVOUS SYSTEM AND BRAIN DISORDERS; GLUTAMATE UPTAKE INHIBITORS | SUNTORY LIMITED (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0948962-A2 | Beta-hydroxyaspartic acid derivatives | SUNTORY LIMITED (JP) | 1999-10-13 | — | — | EP | disclosed |