SCHEMBL999110

SCHEMBL999110

C[C@H](O)[C@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSK P43235 9/20 0.51
CTSS P25774 5/20 0.51
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CYP2D6 P10635 1/20 0.46
APP P05067 1/20 0.45
TSHR P16473 1/20 0.43
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
CTSL P07711 2/20 0.42
CTSB P07858 2/20 0.42
PREP P48147 1/20 0.41
TRPA1 O75762 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312767 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL708581 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL16710007 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL1312765 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL708582 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL693616 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL1311851 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL23794778 0.89 CTSK (0.49) CTSKCTSSCA1CA2CA7
SCHEMBL30718547 0.89 CTSK (0.49) CTSKCTSSCA1CA2CA7
SCHEMBL23794776 0.89 CTSK (0.49) CTSKCTSSCA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702033-A1 DESMURAMYLPEPTIDE DIACIDS AS NOD2 AGONISTS AND USE THEREOF Imhotex Limited (GB) 2026-03-04 EP disclosed
EP-3681875-B1 CYCLIC PEPTIDE ANTIBIOTICS HOFFMANN LA ROCHE (CH) 2026-01-14 EP disclosed
US-20250388601-A1 Compounds, Compositions and Methods DENALI THERAPEUTICS INC. (US) 2025-12-25 US disclosed
WO-2025235719-A1 DIMERIC SMAC MIMETICS USEFUL IN HIV THERAPY VIIV HEALTHCARE COMPANY (US) 2025-11-13 WO disclosed
US-20250304603-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS INC (US) 2025-10-02 US disclosed
US-12358928-B2 Compounds, compositions and methods DENALI THERAPEUTICS INC. (US) 2025-07-15 US disclosed
US-12358951-B2 Cyclic peptide antibiotics GENENTECH, INC. (US) 2025-07-15 US disclosed
CN-111148739-B Cyclic peptide antibiotics 豪夫迈·罗氏有限公司 2025-06-03 CN disclosed
CN-118994190-A Inhibitors of receptor interacting protein kinase 1 戴纳立制药公司 2024-11-22 CN disclosed
CN-118994191-A Inhibitors of receptor interacting protein kinase 1 戴纳立制药公司 2024-11-22 CN disclosed
WO-2003099274-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-12-04 WO disclosed
EP-0336230-B1 Cyclic peptide antagonists of Substance P and Substance K FUJISAWA PHARMACEUTICAL CO (JP) 1997-02-12 EP disclosed
US-5436140-A Cyclic peptides as antagonist, analgesics or antihistamines FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-07-25 US disclosed
US-5217952-A Analgesics, antihistamine FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-06-08 US disclosed
EP-0336230-A2 Cyclic peptide antagonists of Substance P and Substance K FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-10-11 EP disclosed
US-4775670-A BACTERICIDES, ANTIBIOTICS E. R. SQUIBB & SONS, INC. (US) 1988-10-04 US disclosed
EP-0048953-B1 BETA-LACTAM ANTIBIOTICS E.R. Squibb & Sons, Inc. (US) 1988-03-09 EP disclosed
EP-0187355-A1 Process for preparing beta-lactam antibiotics E.R. Squibb & Sons, Inc. (US) 1986-07-16 EP disclosed
US-4551276-A 2-Oxoazetidin-1-yloxymethyl sulfonic acid and analogs E. R. SQUIBB & SONS, INC. (US) 1985-11-05 US disclosed
US-4529698-A Culturing Chromobacterium E. R. SQUIBB & SONS, INC. (US) 1985-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304603-A1 OXABOROLE ESTERS AND USES THEREOF OXA1L, HSD17B12, OXER1 CTSK 3925/4885CTSS 3911/4885CA1 3605/4885
US-20250388601-A1 Compounds, Compositions and Methods AURKC, WEE2, ERBB2 CTSK 1667/4885CTSS 1732/4885CA1 1660/4885
US-12358951-B2 Cyclic peptide antibiotics NPPA, LNPEP, CLPP CTSK 619/4885CTSS 738/4885CA1 4539/4885
US-12358928-B2 Compounds, compositions and methods PIK3CA, PLK1, PIK3CB CTSK 881/4885CTSS 1875/4885CA1 2234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.