Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887123 | 0.85 | GLA (0.49) | GLASMN1; SMN2PAOXKMT2AMEN1 | |
| SCHEMBL39611 | 0.85 | GLA (0.49) | GLASMN1; SMN2PAOXKMT2AMEN1 | |
| SCHEMBL6449843 | 0.83 | GAA (0.46) | GLASMN1; SMN2PAOXKMT2AMEN1 | |
| SCHEMBL8600889 | 0.80 | GLA (0.44) | GLASMN1; SMN2PAOXKMT2AMEN1 | |
| SCHEMBL13318708 | 0.78 | KDM4E (0.47) | GLASMN1; SMN2PAOXKMT2AMEN1 | |
| SCHEMBL317493 | 0.77 | GLA (0.40) | GLASMN1; SMN2PAOXKMT2AMEN1 | |
| SCHEMBL317495 | 0.77 | GLA (0.40) | GLASMN1; SMN2PAOXKMT2AMEN1 | |
| SCHEMBL17983458 | 0.74 | GAA (0.51) | GLASMN1; SMN2PAOXKMT2AMEN1 | |
| Acetic Acid SCHEMBL28231316 | 0.72 | GLA (0.50) | GLASMN1; SMN2PAOXKMT2AMEN1 | |
| SCHEMBL504158 | 0.71 | CD81 (0.39) | PAOXALDH1A1HSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717977-B1 | Fluoride releasing dental composite material | 3M ESPE AG (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-5824720-A | DI OR MULTI(METH)ACRYLATES, INITIATORS, ACTIVATORS, FILLERS AND FLUORIDE COMPLEXES FOR DENTAL FILLING | THERA PATENT GMBH & CO. KG GESELLSCHAFT FUR INDUSTRIELLE SCHUTZRECHTE (DE) | 1998-10-20 | — | — | US | disclosed |
| EP-0717977-A2 | Fluoride releasing dental composite material | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1996-06-26 | — | — | EP | disclosed |