Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20449043 | 0.95 | THRB (0.56) | THRBTSHRALDH1A1TP53HIF1A | |
| Carbamic Acid SCHEMBL25276902 | 0.92 | THRB (0.52) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL28499034 | 0.89 | ALDH1A1 (0.53) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL29315419 | 0.87 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL29315422 | 0.86 | THRB (0.52) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL19804210 | 0.85 | THRB (0.59) | THRBTSHRALDH1A1FFAR1FFAR4 | |
| Urethane SCHEMBL28919284 | 0.85 | THRB (0.46) | THRBTSHRALDH1A1FFAR1FFAR4 | |
| SCHEMBL29315424 | 0.85 | TSHR (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL29315429 | 0.85 | TSHR (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL19730253 | 0.82 | THRB (0.48) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030168657-A1 | Reactive mesogenic azulenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2003-09-11 | — | — | US | claimed |