Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4817067 | 0.94 | KDM4E (0.52) | HTR1AHTR2AHTR7SLC2A1DRD4 | |
| SCHEMBL4818594 | 0.79 | DRD4 (0.51) | HTR1AHTR2AHTR7DRD4 | |
| SCHEMBL4824115 | 0.78 | ALDH1A1 (0.57) | HTR1AHTR2AHTR7DRD4KDM4E | |
| SCHEMBL4823372 | 0.78 | KDM4E (0.52) | HTR1ADRD4KDM4EALDH1A1LMNA | |
| SCHEMBL4823578 | 0.77 | DRD4 (0.52) | DRD4KDM4EALDH1A1TDP1LMNA | |
| SCHEMBL4825079 | 0.73 | PARP1 (0.42) | HTR1ADRD4 | |
| SCHEMBL4825010 | 0.73 | DRD4 (0.48) | HTR1ADRD4KDM4EALDH1A1TDP1 | |
| SCHEMBL3398854 | 0.73 | SIGMAR1 (0.66) | DRD4KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4820489 | 0.72 | HTR2B (0.39) | HTR1ADRD4 | |
| SCHEMBL4819167 | 0.70 | DRD4 (0.57) | HTR1AHTR2AHTR7DRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101994-A1 | FUSED BICYCLIC AROMATIC COMPOUNDS THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-11 | — | — | WO | disclosed |