Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39543 | 0.90 | HSPA5 (0.65) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL76570 | 0.90 | ALDH1A1 (0.54) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9765625 | 0.88 | ALDH1A1 (0.52) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL4558428 | 0.88 | ALDH1A1 (0.52) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10424192 | 0.87 | DHFR (0.49) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL1433745 | 0.86 | HSPA5 (0.56) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL20272914 | 0.86 | ALDH1A1 (0.50) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9475140 | 0.86 | HSPA5 (0.70) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL49284 | 0.86 | ALDH1A1 (0.54) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL11343392 | 0.85 | ALDH1A1 (0.49) | HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770731-B2 | MELT POLYMERIZED BRANCHED POLYCARBONATE WITH NON-NEWTONIAN FLOW BEHAVIOR: GOOD FLOWABILITY AT HIGH SHEAR RATES, AND IS NOT LESS FLOWABLE THAN UNBRANCHED POLYCARBONATE AT LOW SHEAR RATES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-03 | — | — | US | disclosed |
| EP-0137395-A2 | 4-(Hydroxyphenylthio)-benzoates | CIBA-GEIGY AG (CH) | 1985-04-17 | — | — | EP | disclosed |
| EP-0116517-A1 | Ester or anhydride of substituted 4-(hydroxyphenyl-thio)-succinic acid | CIBA-GEIGY AG (CH) | 1984-08-22 | — | — | EP | disclosed |
| EP-0113318-A1 | (4-Hydroxyphenylthio)-imide stabilizers | CIBA-GEIGY AG (CH) | 1984-07-11 | — | — | EP | disclosed |