Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BAX | Q07812 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602190 | 0.81 | CA4 (0.42) | CA4LTA4HTSHRCA5ACA5B | |
| SCHEMBL9719613 | 0.81 | CA4 (0.42) | CA4LTA4HTSHRCA5ACA5B | |
| SCHEMBL6306408 | 0.81 | CA4 (0.42) | CA4LTA4HTSHRCA5ACA5B | |
| SCHEMBL9602185 | 0.81 | CA4 (0.42) | CA4LTA4HTSHRCA5ACA5B | |
| SCHEMBL156818 | 0.78 | AKR1C3 (0.50) | AKR1C3ALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL821031 | 0.78 | AKR1C3 (0.50) | AKR1C3ALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL11151230 | 0.77 | LTA4H (0.36) | CA4LTA4HTSHRCA5ACA5B | |
| SCHEMBL7298493 | 0.77 | CA4 (0.39) | CA4LTA4HTSHRCA5ACA5B | |
| SCHEMBL16807830 | 0.77 | CA4 (0.39) | CA4LTA4HTSHRCA5ACA5B | |
| SCHEMBL7298485 | 0.77 | CA4 (0.39) | CA4LTA4HTSHRCA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341502-A2 | HAIR CONDITIONING COMPOSITIONS AND THEIR USE IN HAIR COLOURING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002047632-A2 | HAIR CONDITIONING COMPOSITIONS COMPRISING AMINOFUNCTIONA POLYSILOXANES | THE PROCTER & GAMBLE COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |