SCHEMBL9719613

SCHEMBL9719613

CC(C)=COc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.42
LTA4H P09960 3/20 0.39
TSHR P16473 1/20 0.39
CA5A P35218 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
NR1H2 P55055 1/20 0.36
BAX Q07812 1/20 0.36
LMNA P02545 1/20 0.35
TTR P02766 1/20 0.35
ALDH1A1 P00352 3/20 0.34
RECQL P46063 1/20 0.34
SRC P12931 1/20 0.34
ALOX15 P16050 1/20 0.34
MAPT P10636 2/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13167017 0.91 LTA4H (0.50) LTA4HTSHRNR1H2BAXLMNA
SCHEMBL4371377 0.87 TTR (0.37) LMNATTRMAPTTP53HPGD
SCHEMBL6306408 0.85 CA4 (0.42) CA4LTA4HTSHRCA5ACA5B
SCHEMBL9602185 0.85 CA4 (0.42) CA4LTA4HTSHRCA5ACA5B
SCHEMBL9602190 0.85 CA4 (0.42) CA4LTA4HTSHRCA5ACA5B
SCHEMBL4368118 0.83 ABL1 (0.37) LMNATTRALDH1A1MTNR1AMTNR1B
SCHEMBL16807830 0.81 CA4 (0.39) CA4LTA4HTSHRCA5ACA5B
SCHEMBL7106698 0.81 CA4 (0.39) CA4LTA4HTSHRCA5ACA5B
SCHEMBL7298493 0.81 CA4 (0.39) CA4LTA4HTSHRCA5ACA5B
SCHEMBL7298485 0.81 CA4 (0.39) CA4LTA4HTSHRCA5ACA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278473-B2 Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-23 US disclosed
US-5166405-A Polymers suitable for use as positive photoresists CIBA-GEIGY CORPORATION (US) 1992-11-24 US disclosed
US-5106932-A Polymers usable as positive photoresists CIBA-GEIGY CORPORATION (US) 1992-04-21 US disclosed
EP-0467841-A2 Benzoic acid ester comprising an olefinically unsaturated substituant CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed
CN-1048217-A 2,3-dihydroxyl-2, a kind of preparation method of 2-dimethyl-7-benzofuran phenol LIU XINJIN (CN) 1991-01-02 CN disclosed
US-4138411-A RUTHENIUM OR OSMIUM CATALYST RHONE-POULENC S. A. (FR) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME OXER1, CBR1, DEGS1 CA4 2405/4885LTA4H 1295/4885TSHR 246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.