SCHEMBL7106823

SCHEMBL7106823

N#Cc1ccc(Oc2c(F)c(C#N)c(C#N)c(F)c2Oc2ccc(C#N)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP15 Q460N3 1/20 0.43
PARP10 Q53GL7 1/20 0.43
PARP2 Q9UGN5 1/20 0.43
PGR P06401 7/20 0.43
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
CYP19A1 P11511 1/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
IL18 Q14116 1/20 0.42
MAOB P27338 1/20 0.42
ALOX5AP P20292 1/20 0.39
FEN1 P39748 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551650 0.83 AR (0.43) PARP15PARP10PARP2PGRKDM4E
SCHEMBL7103435 0.82 KMT2A (0.44) KDM4EMEN1POLBMAPTRAB9A
SCHEMBL31410707 0.81 PARP15 (0.43) PARP15PARP10PARP2PGRKDM4E
SCHEMBL6552310 0.80 AR (0.36) PARP15PARP10PARP2PGRKDM4E
SCHEMBL30784949 0.79 PARP15 (0.42) PARP15PARP10PARP2PGRKDM4E
SCHEMBL7868417 0.79 CYP1A2 (0.45) KDM4ELMNAMEN1POLBMAPT
SCHEMBL31623082 0.79 HPGD (0.48) KDM4ELMNAMEN1POLBMAPT
SCHEMBL7868322 0.78 CA12 (0.44) KDM4EMEN1POLBMAPTRAB9A
SCHEMBL30413391 0.78 HPGD (0.51) PARP15PARP10PARP2KMT2ACA1
SCHEMBL7873493 0.77 L3MBTL1 (0.42) KDM4ELMNAMEN1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934985-B1 Phthalocyanine compound, method for production thereof and use thereof NIPPON CATALYTIC CHEM IND (JP) 2003-07-09 EP disclosed
US-6069244-A EXCELLENT ABILITY TO ABSORB NEAR INFRARED RAY; COMPATIBILITY WITH ACRYLIC RESINS; HEAT RESISTANCE; PHOTOSTABILITY; WEATHERPROOFING; HIGH TRANSMITTANCE TO A VISIBLE LIGHT RAY; HEAT RAY SHIELDING MATERIAL; PLASMA DISPLAY GRADE FILTER NIPPON SHOKUBAI CO., LTD. (JP) 2000-05-30 US disclosed
EP-0934985-A2 Phthalocyanine compound, method for production thereof and use thereof NIPPON SHOKUBAI CO., LTD. (JP) 1999-08-11 EP disclosed