SCHEMBL7868417

SCHEMBL7868417

N#Cc1c(F)c(F)c(Oc2ccc(F)cc2)c(F)c1C#N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2C19 P33261 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 4/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
CYP2D6 P10635 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
HPGD P15428 5/20 0.40
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 1/20 0.37
SQOR Q9Y6N5 1/20 0.36
AR P10275 1/20 0.36
SOS1 Q07889 1/20 0.34
HSPB1 P04792 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7873493 0.86 L3MBTL1 (0.42) CYP1A2CYP3A4CYP2C19SMN1; SMN2KDM4E
SCHEMBL7870128 0.86 ALDH1A1 (0.43) CYP1A2CYP3A4CYP2C19SMN1; SMN2KDM4E
SCHEMBL7106499 0.85 CA12 (0.49) CYP1A2CYP2C19SMN1; SMN2KDM4EMEN1
SCHEMBL29582037 0.83 MEN1 (0.39) CYP1A2CYP3A4CYP2C19SMN1; SMN2KDM4E
SCHEMBL7870170 0.83 MEN1 (0.41) CYP1A2CYP3A4CYP2C19SMN1; SMN2KDM4E
SCHEMBL3619566 0.80 TRPV4 (0.31)
SCHEMBL7106823 0.79 PARP15 (0.43) CYP1A2CYP3A4CYP2C19SMN1; SMN2KDM4E
SCHEMBL3194044 0.79 CA12 (0.50) CYP1A2CYP2C19SMN1; SMN2KDM4EMEN1
SCHEMBL13439997 0.78 TRPV4 (0.30)
SCHEMBL3893589 0.77 ALDH1A1 (0.46) SMN1; SMN2KDM4EMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882768-B1 Method for producing of phthalocyanine compound NIPPON CATALYTIC CHEM IND (JP) 2001-12-19 EP disclosed
US-6034236-A REACTING A PHTHALONITRILE WITH A METAL OXIDE IN PRESENCE OF A SULFONIC ACID CATALYST NIPPON SHOKUBAI CO., LTD. (JP) 2000-03-07 US disclosed
EP-0882768-A2 Method for producing of phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 1998-12-09 EP disclosed