Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994302 | 0.82 | OPRL1 (0.44) | RAB9AKMT2AKDM4EOPRL1 | |
| SCHEMBL7031617 | 0.81 | GRIN2B (0.53) | GRIN2BMEN1RAB9AKMT2AACHE | |
| SCHEMBL7932450 | 0.80 | OPRL1 (0.48) | SLC6A4KDM4EOPRL1 | |
| SCHEMBL3167985 | 0.79 | ADRA1A (0.49) | RAB9AKMT2AKDM4ETSHROPRL1 | |
| SCHEMBL29580963 | 0.79 | ADRA1A (0.49) | RAB9AKMT2AKDM4ETSHROPRL1 | |
| Hydrochloric Acid SCHEMBL7936704 | 0.79 | OPRL1 (0.47) | SLC6A4KDM4EOPRL1 | |
| Hydrochloric Acid SCHEMBL7934160 | 0.79 | OPRL1 (0.47) | SLC6A4KDM4EOPRL1 | |
| Hydrochloric Acid SCHEMBL7934158 | 0.79 | OPRL1 (0.47) | SLC6A4KDM4EOPRL1 | |
| SCHEMBL19192071 | 0.79 | GRIN2B (0.57) | GRIN2BMEN1RAB9AKMT2AACHE | |
| SCHEMBL8003101 | 0.78 | DRD4 (0.42) | RAB9AKDM4EOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341753-A1 | CYCLOHEXYL(ALKYL)-PROPANOLAMINES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002044139-A1 | CYCLOHEXYL(ALKYL)-PROPANOLAMINES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |