Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7934160 | 0.99 | OPRL1 (0.47) | OPRL1KDM4ESMYD3HCRTR2DRD4 | |
| Hydrochloric Acid SCHEMBL7936704 | 0.99 | OPRL1 (0.47) | OPRL1KDM4ESMYD3HCRTR2DRD4 | |
| Hydrochloric Acid SCHEMBL7934158 | 0.99 | OPRL1 (0.47) | OPRL1KDM4ESMYD3HCRTR2DRD4 | |
| SCHEMBL7994302 | 0.82 | OPRL1 (0.44) | OPRL1KDM4EHCRTR2DRD4ADRA1A | |
| SCHEMBL8003101 | 0.81 | DRD4 (0.42) | OPRL1KDM4EHCRTR2DRD4ADRA1A | |
| SCHEMBL7106832 | 0.80 | GRIN2B (0.49) | OPRL1KDM4ESLC6A4 | |
| SCHEMBL3167985 | 0.79 | ADRA1A (0.49) | OPRL1KDM4EHCRTR2DRD4ADRA1A | |
| SCHEMBL29580963 | 0.79 | ADRA1A (0.49) | OPRL1KDM4EHCRTR2DRD4ADRA1A | |
| SCHEMBL8178976 | 0.77 | OPRL1 (0.43) | OPRL1KDM4EHCRTR2DRD4ADRA1A | |
| SCHEMBL7714987 | 0.76 | KDM4E (0.44) | KDM4EDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235759-B1 | BENIGN PROSTATIC HYPERPLASIA; HYPOTENSIVE AGENTS | MERCK & CO., INC. | 2001-05-22 | — | — | US | disclosed |
| WO-2000025782-A1 | DIHYDROPYRIDINONES AND PYRROLINONES USEFUL AS ALPHA 1A ADRENOCEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |