SCHEMBL7106883

SCHEMBL7106883

Cc1c(Cl)cccc1S(=O)(=O)c1cccc(Cl)c1C

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 6/20 0.51
EDNRA P25101 3/20 0.49
EDNRB P24530 2/20 0.49
ALDH1A1 P00352 2/20 0.46
SLC40A1 Q9NP59 1/20 0.45
CCR4 P51679 1/20 0.42
PGR P06401 1/20 0.42
MCOLN3 Q8TDD5 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3277048 0.84 HSD11B1 (0.50) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL2046745 0.84 HSD11B1 (0.50) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL350041 0.84 HSD11B1 (0.50) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL618887 0.83 HSD11B1 (0.49) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL6038928 0.83 HSD11B1 (0.49) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL974591 0.83 HSD11B1 (0.49) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL4615891 0.83 HSD11B1 (0.49) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL21388392 0.82 HSD11B1 (0.49) HSD11B1EDNRAEDNRBSLC40A1MEN1
Hydrochloric Acid SCHEMBL11155347 0.81 HSD11B1 (0.47) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL31527823 0.81 HSD11B1 (0.48) HSD11B1EDNRAEDNRBALDH1A1SLC40A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed