Sugi Predict

Sugi Predict / Compounds / SCHEMBL350041

SCHEMBL350041

SCHEMBL350041

Cc1c(Cl)cccc1S(=O)(=O)Cl

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 6/20 0.50
▸ EDNRA P25101 3/20 0.47
▸ EDNRB P24530 2/20 0.47
▸ ALDH1A1 P00352 2/20 0.45
▸ SLC40A1 Q9NP59 1/20 0.44
▸ CCR4 P51679 1/20 0.41
▸ MCOLN3 Q8TDD5 1/20 0.40
▸ NR3C1 P04150 1/20 0.38
▸ PGR P06401 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11348878 0.86 ALDH1A1 (0.40) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL7106883 0.84 HSD11B1 (0.51) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL2046745 0.83 HSD11B1 (0.50) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL3277048 0.83 HSD11B1 (0.50) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL11762263 0.81 ALDH1A1 (0.52) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL618887 0.81 HSD11B1 (0.49) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL6038928 0.81 HSD11B1 (0.49) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL974591 0.81 HSD11B1 (0.49) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL4615891 0.81 HSD11B1 (0.49) HSD11B1EDNRAEDNRBALDH1A1SLC40A1
SCHEMBL691798 0.80 KMT2A (0.45) HSD11B1EDNRAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 494 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117263832-A Synthesis method of 2-chloro-4-methylsulfonyl benzoic acid 辽宁龙田化工科技有限公司 2023-12-22 — — CN claimed
CN-103319489-B Triazolopyrimidine sulfonamide compound, and synthetic method and application thereof UNIV HEILONGJIANG 2015-04-08 — — CN claimed
CN-103319489-A Triazolopyrimidine sulfonamide compound, and synthetic method and application thereof UNIV HEILONGJIANG 2013-09-25 — — CN claimed
EP-1506176-B1 AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PFIZER ITALIA SRL (IT) 2013-04-24 — — EP claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 — — EP claimed
US-20260137697-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF UNIV DE MONTREAL (CA) 2026-05-21 — — US disclosed
CN-117177975-B Pyrimido [5,4, D ] pyrimidine compounds, compositions comprising the same and uses thereof 蒙特利尔大学 2026-05-19 — — CN disclosed
WO-2025243317-A1 SUBSTITUTED BICYCLIC SULFONAMIDE DERIVATIVES AS MODULATORS OF CBL-B JUBILANT BIOSYS LIMITED (IN) 2025-11-27 — — WO disclosed
US-12479842-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease UNIVERSITE DE MONTREAL (CA) 2025-11-25 — — US disclosed
US-20250270207-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE UNIVERSITE DE MONTREAL (CA) 2025-08-28 — — US disclosed
EP-4602047-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF The Universite de Montreal (CA) 2025-08-20 — — EP disclosed
CN-120035595-A Thiazolo [5,4-d ] pyrimidine compounds, compositions comprising the same and uses thereof 蒙特利尔大学 2025-05-23 — — CN disclosed
WO-1994027979-A1 SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN IMMUNOPHARMACEUTICS, INC. (US) 1994-12-08 — — WO disclosed
CN-1084515-A Phenyl sulfamoyl endothelium (endothelin) antagonistic SQUIBB & SONS INC (US) 1994-03-30 — — CN disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 — — US disclosed
CN-1066266-A PHOSPHOSULFONATE HERBICIDES ROHM & HAAS (US) 1992-11-18 — — CN disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 — — EP disclosed
EP-0038458-B1 4-HYDROXY-1,2-BENZISOTHIAZOL-3(2H)-ONE-1,1-DIOXIDE, THEIR SALTS, THEIR PREPARATION AND THEIR UTILIZATION Dr. Karl Thomae GmbH (DE) 1983-09-21 — — EP disclosed
US-4404230-A ARTICIFIAL SWEETENERS DR. KARL THOMAE GMBH (DE) 1983-09-13 — — US disclosed
EP-0038458-A1 4-Hydroxy-1,2-benzisothiazol-3(2H)-one-1,1-dioxide, their salts, their preparation and their utilization Dr. Karl Thomae GmbH (DE) 1981-10-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270207-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE BRAF, NRAS, KRAS HSD11B1 2854/4885EDNRA 3969/4885EDNRB 3039/4885
US-20260137697-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF NRAS, KRAS, BRAF HSD11B1 1385/4885EDNRA 2926/4885EDNRB 2901/4885
US-12479842-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease BRAF, NRAS, DPYD HSD11B1 2892/4885EDNRA 3974/4885EDNRB 3042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.