SCHEMBL7106903

SCHEMBL7106903

O=c1[nH]c2c(c(=O)[nH]1)C(=S)CC=C2

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYMP P19971 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4579905 0.64 KDM4E (0.32)
SCHEMBL9573555 0.64 TYMP (0.33) TYMP
SCHEMBL31000007 0.60 ALDH1A1 (0.38)
SCHEMBL3423553 0.56
SCHEMBL13653521 0.56 ALDH1A1 (0.33)
SCHEMBL8321438 0.55
SCHEMBL3718306 0.53 TYMP (0.31) TYMP
SCHEMBL5323960 0.52
SCHEMBL10820339 0.51 APAF1 (0.39) TYMP
SCHEMBL10606995 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112624984-B 4-thio quinazoline diketone derivative and preparation method thereof 内蒙古工业大学 2022-06-10 CN disclosed
CN-112624984-A 4-thio quinazoline diketone derivative and preparation method thereof 内蒙古工业大学 2021-04-09 CN disclosed
EP-0922037-B1 PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES DU PONT (US) 2003-10-01 EP disclosed
EP-1344775-A1 Preparation of fungicidal quinazolinones and useful intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-09-17 EP disclosed
US-6166208-A Preparation of fungicidal quinazolinones and useful intermediates E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-12-26 US disclosed
EP-0922037-A1 PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-06-16 EP disclosed
WO-1997048684-A1 PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-12-24 WO disclosed
US-4562322-A SULFUR HEXAFLUORIDE, RESIN INSULATOR BLEND OF POLYOLEFIN AND NITROGEN-CONTAINING POLYMER, HEAT RESISTANT HITACHI, LTD. (JP) 1985-12-31 US disclosed