SCHEMBL7106918

SCHEMBL7106918

CCNC(=O)C(=O)NN=C(c1ccc(Cl)cc1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 5/20 0.38
ENPP3 O14638 4/20 0.38
ENPP2 Q13822 3/20 0.38
CXCR2 P25025 1/20 0.37
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRB2 P47870 1/20 0.36
GABRA4 P48169 1/20 0.36
GABRA6 Q16445 1/20 0.36
PSEN1 P49768 3/20 0.36
PSEN2 P49810 3/20 0.36
APH1B Q8WW43 3/20 0.36
NCSTN Q92542 3/20 0.36
APH1A Q96BI3 3/20 0.36
PSENEN Q9NZ42 3/20 0.36
PLAAT3 P53816 1/20 0.36
PLAAT5 Q96KN8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7104414 0.86 ENPP1 (0.41) ENPP1ENPP3ENPP2CXCR2PSEN1
SCHEMBL7104412 0.86 ENPP1 (0.41) ENPP1ENPP3ENPP2CXCR2PSEN1
SCHEMBL11032658 0.85 MEN1 (0.41) ENPP1ENPP3ENPP2CXCR2PSEN1
SCHEMBL11032656 0.85 MEN1 (0.41) ENPP1ENPP3ENPP2CXCR2PSEN1
SCHEMBL10973313 0.84 MEN1 (0.42) ENPP1ENPP3ENPP2CXCR2PSEN1
SCHEMBL9079609 0.84 MEN1 (0.42) ENPP1ENPP3ENPP2CXCR2PSEN1
SCHEMBL11033152 0.83 ALDH1A1 (0.46) ENPP1ENPP3ENPP2CXCR2PSEN1
SCHEMBL9079636 0.83 SMN1; SMN2 (0.44) ENPP1ENPP3ENPP2CXCR2MEN1
SCHEMBL11033155 0.83 ALDH1A1 (0.46) ENPP1ENPP3ENPP2CXCR2PSEN1
SCHEMBL8535057 0.82 ALDH1A1 (0.53) ENPP1ENPP3ENPP2CXCR2PSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030087958-A1 Hydrazine oxoacetamide derivative and insecticide AGRO-KANESHO CO., LTD. (JP) 2003-05-08 US disclosed
US-6399659-B2 EFFECTIVE AT LOW CONCENTRATIONS AGRO-KANESHO CO., LTD. (JP) 2002-06-04 US disclosed
US-20010044464-A1 Hydrazine oxoacetamide derivative and insecticide AGRO-KANESHO CO., LTD. (JP) 2001-11-22 US disclosed
EP-1123920-A1 HYDRAZINOOXOACETAMIDE DERIVATIVES AND INSECTICIDE Agro-Kanesho Co. Ltd. (JP) 2001-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087958-A1 Hydrazine oxoacetamide derivative and insecticide DDT, CYP2E1, HCN1 ENPP1 3689/4885ENPP3 3786/4885ENPP2 3531/4885
US-20010044464-A1 Hydrazine oxoacetamide derivative and insecticide DDT, CYP2E1, HCN1 ENPP1 3689/4885ENPP3 3786/4885ENPP2 3531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.