Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353115 | 0.87 | MEN1 (0.61) | MEN1KMT2AALOX15LMNAHSD17B10 | |
| SCHEMBL7512444 | 0.83 | MEN1 (0.52) | MEN1KMT2AALOX15LMNAHSD17B10 | |
| SCHEMBL8053447 | 0.81 | MEN1 (0.50) | MEN1KMT2AALOX15LMNAHSD17B10 | |
| SCHEMBL11174634 | 0.81 | MEN1 (0.50) | MEN1KMT2AALOX15LMNAHSD17B10 | |
| SCHEMBL3352927 | 0.79 | LMNA (0.43) | MEN1KMT2AALOX15LMNAHSD17B10 | |
| SCHEMBL24214239 | 0.79 | MEN1 (0.53) | MEN1KMT2AALOX15LMNAHSD17B10 | |
| SCHEMBL29177162 | 0.79 | MEN1 (0.48) | MEN1KMT2AALOX15LMNAHSD17B10 | |
| SCHEMBL29082258 | 0.79 | MEN1 (0.53) | MEN1KMT2ALMNAHSD17B10CYP4F2 | |
| SCHEMBL7509536 | 0.79 | MEN1 (0.53) | MEN1KMT2AALOX15LMNAHSD17B10 | |
| SCHEMBL17056059 | 0.78 | MEN1 (0.52) | MEN1KMT2AALOX15LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1046638-B1 | Process for the preparation of aminoacid derivatives | DEGUSSA (DE) | 2003-10-01 | — | — | EP | disclosed |
| US-6399809-B1 | FROM MALONIC ACID MONOESTER AMIDE | DEGUSSA AG (DE) | 2002-06-04 | — | — | US | disclosed |
| EP-1046638-A2 | Process for the preparation of aminoacid derivatives | Degussa-Hüls Aktiengesellschaft (DE) | 2000-10-25 | — | — | EP | disclosed |