Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.55 |
| ▸ | S100A4 | P26447 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598895 | 0.89 | PTPRC (0.56) | PTPRCS100A4CA9CA1CA2 | |
| SCHEMBL15442560 | 0.85 | PTPRC (0.55) | PTPRCS100A4CA9CA1CA2 | |
| SCHEMBL29370560 | 0.85 | PTPRC (0.55) | PTPRCS100A4CA9CA1CA2 | |
| SCHEMBL9158448 | 0.84 | PTPRC (0.64) | PTPRCS100A4CA9CA1CA2 | |
| SCHEMBL8427282 | 0.83 | PTPRC (0.50) | PTPRCS100A4CA9CA1CA2 | |
| SCHEMBL8427283 | 0.80 | PTPRC (0.46) | PTPRCS100A4CA9CA1CA2 | |
| SCHEMBL5886292 | 0.78 | PTPRC (0.56) | PTPRCS100A4CA9CA1CA2 | |
| SCHEMBL9122070 | 0.77 | HIF1A (0.53) | PTPRCS100A4CA9CA1TDP1 | |
| SCHEMBL4233516 | 0.72 | CA9 (0.62) | PTPRCS100A4CA9CA1TDP1 | |
| SCHEMBL11207794 | 0.71 | PTPRC (0.83) | PTPRCS100A4CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101005761-B | Imazalil compositions comprising alkoxylated amines | JANSSEN PHARMACEUTICA NV | 2010-06-16 | — | — | CN | disclosed |
| CN-101005761-A | Imazalil compositions comprising alkoxylated amines | JANSSEN PHARMACEUTICA NV (BE) | 2007-07-25 | — | — | CN | disclosed |
| EP-0923543-B1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2003-09-24 | — | — | EP | disclosed |
| US-6083986-A | Potassium channel inhibitors | ICAGEN, INC. (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0923543-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004521-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1998-02-05 | — | — | WO | disclosed |