Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.55 |
| ▸ | S100A4 | P26447 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15442560 | 1.00 | PTPRC (0.55) | PTPRCS100A4CA1CA2CA7 | |
| SCHEMBL5886292 | 0.89 | PTPRC (0.56) | PTPRCS100A4CA1CA2CA7 | |
| SCHEMBL7106993 | 0.85 | PTPRC (0.55) | PTPRCS100A4CA1CA2CA7 | |
| SCHEMBL9158448 | 0.84 | PTPRC (0.64) | PTPRCS100A4CA1CA2CA7 | |
| SCHEMBL8598895 | 0.78 | PTPRC (0.56) | PTPRCS100A4CA1CA2CA7 | |
| SCHEMBL9122070 | 0.77 | HIF1A (0.53) | PTPRCS100A4CA1CA9TDP1 | |
| SCHEMBL8893107 | 0.75 | PTPRC (0.49) | PTPRCS100A4CA1CA2CA7 | |
| SCHEMBL8427282 | 0.73 | PTPRC (0.50) | PTPRCS100A4CA1CA2CA7 | |
| SCHEMBL4445375 | 0.72 | CES1 (0.55) | PTPRCS100A4CA1CA2CA7 | |
| SCHEMBL2772220 | 0.71 | PTPRC (0.83) | PTPRCS100A4CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188907-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2023-06-07 | — | — | EP | disclosed |
| WO-2022023460-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2022-02-03 | — | — | WO | disclosed |