Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 7/20 | 0.50 |
| ▸ | S100A4 | P26447 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427283 | 0.96 | PTPRC (0.46) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL8598895 | 0.94 | PTPRC (0.56) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL7106993 | 0.83 | PTPRC (0.55) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL5886292 | 0.80 | PTPRC (0.56) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL29370560 | 0.73 | PTPRC (0.55) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL15442560 | 0.73 | PTPRC (0.55) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL9158448 | 0.72 | PTPRC (0.64) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL9122070 | 0.69 | HIF1A (0.53) | PTPRCS100A4ACHECA9CA1 | |
| 1,2-Naphthoquinone SCHEMBL9225602 | 0.69 | PTPRC (0.83) | PTPRCS100A4BCHEACHECES1 | |
| 1,2-Naphthoquinone SCHEMBL29368763 | 0.69 | PTPRC (0.83) | PTPRCS100A4BCHEACHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698600-B1 | Composition, method and test device for determining the presence of leukocyte cells, esterase or protease in a test sample | BAYER AG (US) | 1999-11-10 | — | — | EP | disclosed |
| US-5512450-A | TEST PAD COMPRISING CARRIER MATRIX WITH HOMOGENEOUSLY INCORPORATED REAGENT INCLUDING HYDROXY-BLOCKED LACTATE ESTER WHICH GENERATES COMPOUND PROVIDING DETECTABLE RESPONSE WHEN HYDROLYZED, BUFFER | BAYER CORPORATION (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0698600-A1 | Composition, method and test device for determining the presence of leukocyte cells, esterase or protease in a test sample | Bayer Corporation (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5464739-A | Urinalysis, hydrolysis of lactate ester | BAYER CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |