Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 13/20 | 0.63 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.63 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155284 | 0.98 | FDPS (0.62) | FDPSSMPD1GGPS1LPAR1LPAR3 | |
| SCHEMBL7551569 | 0.90 | FDPS (0.53) | FDPSSMPD1GGPS1LPAR3 | |
| SCHEMBL5689723 | 0.90 | FDPS (0.70) | FDPSSMPD1GGPS1LPAR1LPAR3 | |
| SCHEMBL4094991 | 0.78 | FDPS (1.00) | FDPSSMPD1GGPS1LPAR1LPAR3 | |
| SCHEMBL11773363 | 0.78 | FDPS (1.00) | FDPSSMPD1GGPS1LPAR1LPAR3 | |
| SCHEMBL293180 | 0.78 | FDPS (1.00) | FDPSSMPD1GGPS1LPAR1LPAR3 | |
| SCHEMBL11803650 | 0.78 | FDPS (1.00) | FDPSSMPD1GGPS1LPAR1LPAR3 | |
| SCHEMBL11793619 | 0.78 | FDPS (1.00) | FDPSSMPD1GGPS1LPAR1LPAR3 | |
| SCHEMBL4088168 | 0.78 | FDPS (1.00) | FDPSSMPD1GGPS1LPAR1LPAR3 | |
| SCHEMBL11329196 | 0.78 | FDPS (1.00) | FDPSSMPD1GGPS1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083313-A1 | Treatment of breast cancer with a liposome mixture comprising an antineoplastic alkylphospholipid and water- or lipid-soluble antiestrogen agents | MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2003-05-01 | — | — | US | claimed |
| EP-1135193-B1 | AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN | MAX DELBRUECK CENTRUM (DE) | 2002-10-30 | — | — | EP | claimed |
| EP-1135193-A1 | AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) | 2001-09-26 | — | — | EP | claimed |
| WO-2000033917-A1 | AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2000-06-15 | — | — | WO | claimed |
| US-20030083313-A1 | Treatment of breast cancer with a liposome mixture comprising an antineoplastic alkylphospholipid and water- or lipid-soluble antiestrogen agents | MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2003-05-01 | — | — | US | disclosed |
| EP-1135193-B1 | AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN | MAX DELBRUECK CENTRUM (DE) | 2002-10-30 | — | — | EP | disclosed |